The clinical assessment of apraxia.

To cite: Cassidy A. Pract Neurol 2016;16:317–322. INTRODUCTION Neurologists are familiar with the standard definition of apraxia: ‘an inability to perform a motor task that cannot be adequately explained by motor weakness, sensory loss or a lack of understanding’. Being a definition of exclusion, this has led to a bewildering number of motor disorders being described as forms of apraxia, despite many of these failing to capture the essence of what apraxia really is: a disorder of motor cognition. Apraxia reflects an impairment of the storage and transformation of motor representations in the brain, either through degradation of the semantic knowledge of gestures and tool use or through inability to translate the neural representations of higher level goals accurately into lower level patterns of muscle activation and inhibition.